For buyers dreaming of lakefront living in North Florida, few settings offer the combination of recreation, natural beauty, and peaceful surroundings found on Lake Santa Fe.
Located at 298 SE 5th Avenue in Melrose, Florida, this exceptional waterfront home offers approximately 100 feet of lake frontage, a private dock and boat lift, expansive outdoor living spaces, and a beautifully updated interior designed to make the most of its incredible setting.
Offered at $1,349,000, this 3-bedroom, 3-bath home provides 3,360 square feet of living space and plenty of room for family, friends, and entertaining.
A Lake Santa Fe Home Designed Around the View
From the moment you step inside, it is clear that the lake is the centerpiece of this home.
The open-concept main living area brings together the custom kitchen, dining area, and living room, creating an inviting gathering space with expansive views across Lake Santa Fe.
Large windows bring the outdoors in, while direct access to the upper deck makes it easy to transition from indoor living to the waterfront setting.
One of the home's most distinctive features is the see-through gas fireplace, which connects the interior living area with the outdoor space. Whether you're entertaining guests or enjoying a quiet evening at home, the layout was designed to keep the lake within view.
More Than 3,300 Square Feet for Living and Entertaining
With 3,360 square feet, this home offers much more than its three bedrooms and three bathrooms.
A loft provides additional sleeping accommodations for up to four guests, while the library and home office features a cleverly concealed Murphy bed hidden behind custom bookcases.
According to the listing, the home's various sleeping spaces can accommodate up to 12 guests in beds, making it particularly well suited for owners who frequently host family and friends.
The library itself overlooks the backyard and Lake Santa Fe, providing an impressive setting for working from home, reading, or simply enjoying the view.
An Entertainment Space Made for Gathering
One of the highlights of 298 SE 5th Avenue is its dedicated entertainment room.
This spacious area provides a place to gather away from the main living room and features a pool table, wet bar, large sectional, custom fishing pole storage cabinet, and EuroCave wine cooler.
Whether you're hosting friends after a day on the lake, spending an evening indoors, or gathering with family for a weekend getaway, the home offers multiple spaces designed for entertaining.
Approximately 100 Feet of Lake Santa Fe Frontage
Of course, the defining feature of this property is outside.
The approximately 100-foot-wide lakefront lot gives the property a substantial presence along Lake Santa Fe and provides direct access to the water.
A private dock and boat lift make it easy to incorporate boating and fishing into everyday life. Instead of loading up the vehicle and heading to a public launch, the lake is right outside your door.
Lake Santa Fe is known throughout the North Florida Lake Region for its recreational opportunities and natural setting. For buyers specifically searching for a home where boating, fishing, and time on the water can become part of their everyday lifestyle, direct lake frontage can make all the difference.
Outdoor Living With Incredible Sunset Views
Waterfront living isn't only about being on the water.
Sometimes the best part is simply sitting back and enjoying it.
The home's outdoor spaces provide opportunities to relax, entertain, and take in the surrounding scenery. The upper deck offers elevated lake views, while the dock provides another place to enjoy the shoreline.
A fire pit adds another gathering area for cooler evenings, and the property is equipped with front and rear irrigation.
The listing also notes abundant wildlife and year-round sunset views from the dock, providing an ever-changing backdrop to everyday life.
A Custom Kitchen at the Center of the Home
The kitchen is positioned at the heart of the open-concept living space and includes features designed for both everyday cooking and entertaining.
A large kitchen island, breakfast bar, eat-in space, gas cooktop, and open layout keep the kitchen connected to the dining and living areas.
Major appliances include a dishwasher, gas cooktop, ice maker, microwave, refrigerator, and wine cooler.
Instead of separating the person preparing dinner from everyone else, the layout allows the kitchen to remain part of the gathering—with Lake Santa Fe just beyond.
Why Buyers Search for Homes on Lake Santa Fe
Lake Santa Fe real estate has a unique appeal because buyers aren't simply purchasing a house. They're purchasing access to a lifestyle that can be difficult to recreate elsewhere.
For some buyers, a Lake Santa Fe property becomes a full-time residence. For others, it becomes the place where family and friends gather on weekends, holidays, and throughout the summer.
The combination of waterfront recreation, natural surroundings, and the small-town atmosphere of the Melrose area makes this part of North Florida particularly distinctive.
And unlike simply living near a lake, owning direct waterfront property means the experience begins in your own backyard.
Property Details at a Glance
298 SE 5th Avenue, Melrose, FL 32666
- Offered at $1,349,000
- 3 bedrooms
- 3 bathrooms
- 3,360 square feet
- 0.43-acre lot
- Approximately 100 feet of lake frontage
- Private dock
- Boat lift
- Open-concept living area
- Custom kitchen
- Vaulted ceilings
- Double-sided gas fireplace
- Library/home office with concealed Murphy bed
- Loft with additional sleeping accommodations
- Entertainment room with wet bar
- EuroCave wine cooler
- Pool table
- Upper deck
- Fire pit
- Central air
Is Lake Santa Fe Living Right for You?
If your ideal Florida home involves stepping outside and seeing the water, keeping your boat at your own dock, entertaining friends and family, and ending the day with a sunset over the lake, this property offers an opportunity worth exploring.
The combination of 3,360 square feet of living space, approximately 100 feet of waterfront, a private dock and boat lift, flexible guest accommodations, and multiple entertainment spaces creates a home designed to be enjoyed throughout the year.
For buyers searching for Lake Santa Fe homes for sale, luxury lakefront homes in Melrose, or waterfront real estate in North Florida, 298 SE 5th Avenue deserves a closer look.
See 298 SE 5th Avenue for Yourself
Photos can showcase the home, but a property like this is best experienced in person.
View the complete listing, browse additional photos and property information, or request a private showing through CB Isaac Realty:
View 298 SE 5th Avenue on CB Isaac Realty
CB Isaac Realty
352-475-2199
Courtesy of Susan Smith and CB Isaac Realty

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